Byron is a town in Big Horn County, Wyoming, United States. The population was 593 at the 2010 census.
According to the United States Census Bureau, the town has a total area of 0.96 square miles (2.49 km2), of which, 0.91 square miles (2.36 km2) of it is land and 0.05 square miles (0.13 km2) is water.
The first settlement at Byron was made ca. 1898. The community has the name of Byron Sessions, a Mormon leader.
As of the census of 2010, there were 593 people, 210 households, and 161 families living in the town. The population density was 651.6 inhabitants per square mile (251.6/km2). There were 238 housing units at an average density of 261.5 per square mile (101.0/km2). The racial makeup of the town was 97.1% White, 0.2% Native American, 1.9% from other races, and 0.8% from two or more races. Hispanic or Latino of any race were 12.5% of the population.
There were 210 households, of which 38.6% had children under the age of 18 living with them, 60.0% were married couples living together, 12.4% had a female householder with no husband present, 4.3% had a male householder with no wife present, and 23.3% were non-families.