Hypoluxo is a town in Palm Beach County, Florida, United States. The population was 2,588 at the 2010 census. As of 2018, the population recorded by the U.S. Census Bureau was 2,783. Hypoluxo Scrub Natural Area is a protected landscape.
The origin of the name "Hypoluxo" is disputed. One theory analyzed the name as composed of the Greek root "hypo-" (under, below average) and the Latin "lux" (light). Hannibel Pierce settled on Hypoluxo Island with his family in 1873. His son, Charlie W. Pierce reported that a Seminole woman told his mother that the Seminole name for Lake Worth was Hypoluxo, which he thought meant 'island', or as he put it using his marginal command of the English language: "water all around, no get out". The name that the Pierces wrote as "Hypoluxo" was given as "Opoloccha" in a history posted by the Town of Hypluxo. J. Clarence Simpson, citing William A. Read, states that the name is from the Creek-Seminole Hapo, meaning "mound" and Plotski, meaning "round", thus "round mound".