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Palo Alto is a borough in Schuylkill County, Pennsylvania, United States. The population was 1,032 at the 2010 census. The borough stretches along the south bank of the Schuylkill River. Bacon Street is the main street of town. The borough shares Pottsville's ZIP Code, telephone exchanges, and school district. The borough maintains its own fire department and police department.
Palo Alto is located at 40°41′16″N 76°10′16″W.
According to the United States Census Bureau, the borough has a total area of 1.1 square miles (2.8 km2), all of it land.
As of the census of 2000, there were 1,052 people, 444 households, and 306 families living in the borough. The population density was 995.9 people per square mile (383.2/km2). There were 478 housing units at an average density of 452.5 per square mile (174.1/km2).