Independence is a home rule-class city in Kenton County, Kentucky, in the United States. It is one of its county's two seats of government. The population was 24,757 at the time of the 2010 U.S. census, up from 14,982 at the 2000 census.
The current mayor of Independence is Chris Reinersman.
Independence is located in central Kenton County at 38°57′13″N 84°32′49″W (38.953668, -84.546990). It is bordered to the northwest by Elsmere, to the north by Erlanger and Covington, and to the northeast by Ryland Heights. The western border of Independence follows the Boone County line, and the city of Florence in Boone County borders the far northwestern end of Independence.
The original center of Independence is in the southeast part of the city, along Madison Pike. Kentucky Route 17, a four-lane divided highway, passes just east of the city center, leading north 11 miles (18 km) to downtown Covington and south 27 miles (43 km) to Falmouth.
According to the United States Census Bureau, Independence has a total area of 17.70 square miles (45.83 km2), of which 17.44 square miles (45.16 km2) are land and 0.26 square miles (0.67 km2), or 1.45%, are water.