Wickliffe is a city in Lake County, Ohio, United States. The population was 12,750 at the 2010 census.
A post office called Wickliffe has been in operation since 1843. The city was named after Charles A. Wickliffe, 11th United States Postmaster General.
Wickliffe is located at 41°36′34″N 81°28′22″W (41.609398, -81.472905).
According to the United States Census Bureau, the city has a total area of 4.66 square miles (12.07 km2), of which 4.64 square miles (12.02 km2) is land and 0.02 square miles (0.05 km2) is water.
It is landlocked due to the neighboring cities of Euclid and Willowick (to which it partially lent its name); it also borders Willoughby. Eastlake and Richmond Heights are not quite adjacent to it, but are close.
As of the census of 2010, there were 12,750 people, 5,455 households, and 3,426 families living in the city. The population density was 2,747.8 inhabitants per square mile (1,060.9/km2). There were 5,780 housing units at an average density of 1,245.7 per square mile (481.0/km2). The racial makeup of the city was 92.8% White, 4.5% African American, 0.1% Native American, 0.8% Asian, 0.2% from other races, and 1.6% from two or more races. Hispanic or Latino of any race were 1.2% of the population.