Edwardsville is a borough in Luzerne County, Pennsylvania, United States. The population was 4,816 at the 2010 census.
Edwardsville was first settled in 1768 by settlers from Connecticut. It was later incorporated as a borough in 1884.
Edwardsville is located at 41°15′58″N 75°54′30″W (41.266081, -75.908457).
According to the United States Census Bureau, the borough has a total area of 1.2 square miles (3.1 km2), of which 1.2 square miles (3.0 km2) is land and 0.04 square miles (0.1 km2), or 2.95%, is water. The Susquehanna River makes up the borough’s southern border.
U.S. Route 11 is the only major highway running through Edwardsville.
As of the census of 2000, there were 4,984 people, 2,345 households, and 1,280 families living in the borough. The population density was 4,233.5 people per square mile (1,630.8/km2). There were 2,587 housing units at an average density of 2,197.4 per square mile (846.5/km2).
The racial makeup of the borough was 95.43% White, 2.57% African American, 0.30% Native American, 0.30% Asian, 0.36% from other races, and 1.04% from two or more races. Hispanic or Latino of any race were 1.18% of the population.